Marc Daniel Ryser

Marc Daniel Ryser
  • Assistant Professor in Population Health Sciences
  • Instructor in the Department of Mathematics (Joint)
External address: 1021 Minerva Ave, Apt 2, Durham, NC 27701

Research Areas and Keywords

Biological Modeling
cancer biology, cancer epidemiology, early carcinogenesis, Human papillomavirus, cancer evolution
Computational Mathematics
cancer evolution
PDE & Dynamical Systems
bone biology, pattern formation
cancer biology, cancer epidemiology, early carcinogenesis, Human papillomavirus, cancer evolution

For a detailed description of past and current research projects, please visit

Education & Training
  • Ph.D., McGill University Faculty of Medicine 2011

  • Ph.D., McGill University (Canada) 2011

Selected Grants

Molecular and Radiologic Predictors of Invasion in a DCIS Active Surveillance Cohort awarded by Breast Cancer Research Foundation (Co Investigator). 2018 to 2019

Mathematical Analysis of Spatial Cancer Models awarded by National Science Foundation (Co-Principal Investigator). 2016 to 2019

Ryser, MD, Min, B-H, Siegmund, KD, and Shibata, D. "Spatial mutation patterns as markers of early colorectal tumor cell mobility." Proceedings of the National Academy of Sciences of the United States of America 115.22 (May 14, 2018): 5774-5779. Full Text

Tumor ancestral trees are physically embedded within their tumors

In cancer treatment, metastatic tumors receive equal treatment.  Patients are given the same aggressive therapies when abnormal clusters of cells are discovered early, even if they may be harmless.  In research studies co-led by Duke's Marc Ryser... read more »

New Approach to Bone Remodeling

Kevin Murgas (Biomedical Engineering, Class 2017), started working on this project during a Research Experience for Undergraduates (REU) program in mathematical biology in the summer of 2015. Together with his research mentor, Dr. Marc Ryser, they... read more »

Study: Vaccinating Boys Against HPV Could Prevent Cancer In Men and Women

A mathematical model from Duke University mathematicians suggests more can be done to protect people from the human papilloma virus.    HPV is associated with cervical cancer in women, but can also cause various cancers in men.   Duke mathematician... read more »

Mathematical model suggests select DCIS patients could delay treatment

Active surveillance could be a viable alternative to surgery and radiation for select patients with ductal carcinoma in situ, or DCIS, according to a mathematical model developed by researchers at Duke University.... read more »

Who Can Delay Breast Cancer Treatment? A New Math Model Adds Clues

A new study adds to a growing conversation on the best way to treat women with stage 0 breast cancer read more »