Amanda Randles

Amanda Randles
  • Alfred Winborne and Victoria Stover Mordecai Assistant Professor of Biomedical Sciences
  • Assistant Professor of Biomedical Engineering
  • Assistant Professor of Mathematics (Secondary)
  • Assistant Professor of Computer Science (Secondary)
  • Member of the Duke Cancer Institute
External address: 301 Gross Hall, 140 Science Dr., Durham, NC 27708
Internal office address: Box 90984, Durham, NC 27708
Phone: (919) 660-5425

My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer. 

Education & Training
  • Ph.D., Harvard University 2013

Selected Grants

University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health (Mentor). 1994 to 2022

ORNL Joint Faculty Appointment for Amanda Randles awarded by UT-Battelle, LLC (Principal Investigator). 2017 to 2019

Toward coupled multiphysics models of hemodynamics on leadership systems awarded by National Institutes of Health (Principal Investigator). 2014 to 2019

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Student Support: IEEE Cluster 2018 Conference awarded by National Science Foundation (Principal Investigator). 2018 to 2019

Hartwell Fellowship awarded by Hartwell Foundation (Principal Investigator). 2017 to 2018

Using GPU-Accelerated Computational Fluid Dynamics to Study In-stent Restenosis awarded by Oak Ridge Associated Universities (Principal Investigator). 2016 to 2017

Gounley, J, Draeger, EW, Oppelstrup, T, Krauss, WD, Gunnels, JA, Chaudhury, R, Nair, P, Frakes, D, Leopold, JA, and Randles, A. "Computing the ankle-brachial index with parallel computational fluid dynamics." Journal of Biomechanics (October 19, 2018). Full Text

Hegele, LA, Scagliarini, A, Sbragaglia, M, Mattila, KK, Philippi, PC, Puleri, DF, Gounley, J, and Randles, A. "High-Reynolds-number turbulent cavity flow using the lattice Boltzmann method." Physical Review E 98.4 (October 4, 2018). Full Text

Rafat, M, Stone, HA, Auguste, DT, Dabagh, M, Randles, A, Heller, M, and Rabinov, JD. "Impact of diversity of morphological characteristics and Reynolds number on local hemodynamics in basilar aneurysms." Aiche Journal 64.7 (July 2018): 2792-2802. Full Text

Gounley, J, Vardhan, M, and Randles, A. "A framework for comparing vascular hemodynamics at different points in time." Computer Physics Communications (June 2018). Full Text

Randles, A, Frakes, DH, and Leopold, JA. "Computational Fluid Dynamics and Additive Manufacturing to Diagnose and Treat Cardiovascular Disease." Trends in Biotechnology 35.11 (November 2017): 1049-1061. (Review) Full Text

Dabagh, M, Jalali, P, Butler, PJ, Randles, A, and Tarbell, JM. "Mechanotransmission in endothelial cells subjected to oscillatory and multi-directional shear flow." Journal of the Royal Society, Interface 14.130 (May 2017). Full Text

Randles, A, Draeger, EW, and Bailey, PE. "Massively parallel simulations of hemodynamics in the primary large arteries of the human vasculature." Journal of Computational Science 9 (July 2015): 70-75. Full Text

Whitley, HD, Scullard, CR, Benedict, LX, Castor, JI, Randles, A, Glosli, JN, Richards, DF, Desjarlais, MP, and Graziani, FR. "Lenard-Balescu Calculations and Classical Molecular Dynamics Simulations of Electrical and Thermal Conductivities of Hydrogen Plasmas." Contributions to Plasma Physics 55.2-3 (February 2015): 192-202. Full Text

You, Y, Fu, H, Song, SL, Randles, A, Kerbyson, D, Marquez, A, Yang, G, and Hoisie, A. "Scaling Support Vector Machines on modern HPC platforms." Journal of Parallel and Distributed Computing 76 (February 2015): 16-31. Full Text

Randles, A, and Kaxiras, E. "Parallel in time approximation of the lattice Boltzmann method for laminar flows." Journal of Computational Physics 270 (August 2014): 577-586. Full Text


Herschlag, G, Lee, S, Vetter, JS, and Randles, A. "GPU data access on complex geometries for D3Q19 lattice boltzmann method." August 3, 2018. Full Text

Laurence, TA, Ly, S, Fong, E, Shusteff, M, Randles, A, Gounley, J, and Draeger, E. "Using stroboscopic flow imaging to validate large-scale computational fluid dynamics simulations." January 1, 2017. Full Text

Gounley, J, Draeger, EW, and Randles, A. "Numerical simulation of a compound capsule in a constricted microchannel." January 2017. Full Text

Gounley, J, Chaudhury, R, Vardhan, M, Driscoll, M, Pathangey, G, Winarta, K, Ryan, J, Frakes, D, and Randles, A. "Does the degree of coarctation of the aorta influence wall shear stress focal heterogeneity?." August 2016. Full Text Open Access Copy

Randles, A, Draeger, EW, Oppelstrup, T, Krauss, L, and Gunnels, JA. "Massively parallel models of the human circulatory system." November 15, 2015. Full Text

You, Y, Song, SL, Fu, H, Marquez, A, Dehnavi, MM, Barker, K, Cameron, KW, Randles, AP, and Yang, G. "MIC-SVM: Designing a highly efficient support vector machine for advanced modern multi-core and many-core architectures." January 1, 2014. Full Text

Randles, AP, Kale, V, Hammond, J, Gropp, W, and Kaxiras, E. "Performance analysis of the lattice Boltzmann model beyond Navier-Stokes." October 7, 2013. Full Text

Randles, AP, Rand, DG, Lee, C, Morrisett, G, Sircar, J, Nowak, MA, and Pfister, H. "Massively parallel model of extended memory use in evolutionary game dynamics." October 7, 2013. Full Text