Amanda Randles

Amanda Randles
  • Alfred Winborne and Victoria Stover Mordecai Assistant Professor of Biomedical Sciences
  • Assistant Professor of Biomedical Engineering
  • Assistant Professor of Mathematics (Secondary)
  • Assistant Professor of Computer Science (Secondary)
  • Member of the Duke Cancer Institute
External address: 301 Gross Hall, 140 Science Dr., Durham, NC 27708
Internal office address: Box 90984, Durham, NC 27708
Phone: (919) 660-5425

My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer. 

Education & Training
  • Ph.D., Harvard University 2013

Selected Grants

University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health (Mentor). 1994 to 2022

3D Bioprinted Aneurysm for Intervention Modeling Validation awarded by Lawrence Livermore National Laboratory (Principal Investigator). 2019

Toward coupled multiphysics models of hemodynamics on leadership systems awarded by National Institutes of Health (Principal Investigator). 2014 to 2019

Training in Medical Imaging awarded by National Institutes of Health (Mentor). 2003 to 2019

Student Support: IEEE Cluster 2018 Conference awarded by National Science Foundation (Principal Investigator). 2018 to 2019

ORNL Joint Faculty Appointment for Amanda Randles awarded by UT-Battelle, LLC (Principal Investigator). 2017 to 2019

Hartwell Fellowship awarded by Hartwell Foundation (Principal Investigator). 2017 to 2018

Using GPU-Accelerated Computational Fluid Dynamics to Study In-stent Restenosis awarded by Oak Ridge Associated Universities (Principal Investigator). 2016 to 2017

Lee, S, Gounley, J, Randles, A, and Vetter, JS. "Performance portability study for massively parallel computational fluid dynamics application on scalable heterogeneous architectures(Accepted)." Journal of Parallel and Distributed Computing 129 (July 1, 2019): 1-13. Full Text

Feiger, B, Vardhan, M, Gounley, J, Mortensen, M, Nair, P, Chaudhury, R, Frakes, D, and Randles, A. "Suitability of lattice Boltzmann inlet and outlet boundary conditions for simulating flow in image-derived vasculature." International Journal for Numerical Methods in Biomedical Engineering (March 5, 2019): e3198-null. Full Text

Gounley, J, Vardhan, M, and Randles, A. "A Framework for Comparing Vascular Hemodynamics at Different Points in Time." Computer Physics Communications 235 (February 2019): 1-8. Full Text

Gounley, J, Draeger, EW, Oppelstrup, T, Krauss, WD, Gunnels, JA, Chaudhury, R, Nair, P, Frakes, D, Leopold, JA, and Randles, A. "Computing the ankle-brachial index with parallel computational fluid dynamics." Journal of Biomechanics 82 (January 2019): 28-37. Full Text

Hegele, LA, Scagliarini, A, Sbragaglia, M, Mattila, KK, Philippi, PC, Puleri, DF, Gounley, J, and Randles, A. "High-Reynolds-number turbulent cavity flow using the lattice Boltzmann method." Physical Review E 98.4 (October 4, 2018). Full Text

Rafat, M, Stone, HA, Auguste, DT, Dabagh, M, Randles, A, Heller, M, and Rabinov, JD. "Impact of diversity of morphological characteristics and Reynolds number on local hemodynamics in basilar aneurysms." Aiche Journal 64.7 (July 1, 2018): 2792-2802. Full Text

Randles, A, Frakes, DH, and Leopold, JA. "Computational Fluid Dynamics and Additive Manufacturing to Diagnose and Treat Cardiovascular Disease." Trends in Biotechnology 35.11 (November 2017): 1049-1061. (Review) Full Text

Dabagh, M, Jalali, P, Butler, PJ, Randles, A, and Tarbell, JM. "Mechanotransmission in endothelial cells subjected to oscillatory and multi-directional shear flow." Journal of the Royal Society, Interface 14.130 (May 2017). Full Text

Randles, A, Draeger, EW, and Bailey, PE. "Massively parallel simulations of hemodynamics in the primary large arteries of the human vasculature." Journal of Computational Science 9 (July 1, 2015): 70-75. Full Text


Herschlag, G, Lee, S, Vetter, JS, and Randles, A. "GPU data access on complex geometries for D3Q19 lattice boltzmann method." August 3, 2018. Full Text

Laurence, TA, Ly, S, Fong, E, Shusteff, M, Randles, A, Gounley, J, and Draeger, E. "Using stroboscopic flow imaging to validate large-scale computational fluid dynamics simulations." January 1, 2017. Full Text

Gounley, J, Draeger, EW, and Randles, A. "Numerical simulation of a compound capsule in a constricted microchannel." January 2017. Full Text

Gounley, J, Chaudhury, R, Vardhan, M, Driscoll, M, Pathangey, G, Winarta, K, Ryan, J, Frakes, D, and Randles, A. "Does the degree of coarctation of the aorta influence wall shear stress focal heterogeneity?." August 2016. Full Text Open Access Copy

Randles, A, Draeger, EW, Oppelstrup, T, Krauss, L, and Gunnels, JA. "Massively parallel models of the human circulatory system." November 15, 2015. Full Text

You, Y, Song, SL, Fu, H, Marquez, A, Dehnavi, MM, Barker, K, Cameron, KW, Randles, AP, and Yang, G. "MIC-SVM: Designing a Highly Efficient Support Vector Machine for Advanced Modern Multi-core and Many-Core Architectures." 2014 IEEE International Parallel & Distributed Processing Symposium (IPDPS). May 19, 2014 - May 23, 2014.: IEEE, May 2014. Full Text

You, Y, Song, SL, Fu, H, Marquez, A, Dehnavi, MM, Barker, K, Cameron, KW, Randles, AP, and Yang, G. "MIC-SVM: Designing a highly efficient support vector machine for advanced modern multi-core and many-core architectures." January 1, 2014. Full Text


Bass connections professorships

Vahid Tarokh and Amanda Randles were two of seven faculty members endowed Bass Connections Professorships.  This honor recognizes faculty whose scholaraship and teaching align with the interdisciplinary and collaborative nature of the program, while... read more »